主讲人:韩贤林博士,终身教授
Sanford Burnham Prebys Medical Discovery Institute
题目: Lipid Chemistry and Lipidomics
时间: 2016年11月1日(周二)上午8:00-9:50
地点: 苏州大学独墅湖校区301-1205
邀请人: 生物化学与分子生物学系
主讲人简介:
韩教授曾是美国圣路易斯华盛顿大学医学院助理教授、副教授,现桑福德-伯纳姆医学研究所教授。曾任美国华人质谱学会主席,为脂质组学研究的先驱者之一,拥有多项国际专利。现任国际期刊Lipids副主编,Anal. Biochem.,Chem. Phys. Lipids,J. Lipid Res.等杂志编委。在Trends Biochem. Sci.,Nat. Rev. Endocrinol.,PNAS,J. Lipid Res.等知名杂志发表论文约200篇,被引用15,000多次,H指数达66。
主要科研方向:(1) extension of the shotgun lipidomics technology for increased penetrance into the low abundance regions of a cellular lipidome; (2) identification of the biochemical mechanisms responsible for the sulfatide depletion and ceramide elevation at the earliest stages of Alzheimer’s disease; and (3) identifying the biochemical mechanisms underlying the altered content and composition of lipids in diabetic myocardium and diabetes-induced dementia.
近期代表性论文:
1. Yang, K. and Han, X. (2016) Lipidomics: techniques, applications, and outcomes related to biomedical sciences. Trends Biochem. Sci. In press.
2. Han, X. (2016) Lipidomics for studying metabolism. Nat. Rev. Endocrinol. 12(11):668-679.
3. Palavicini, J.P., Wang, C., Chen, L., Ahmar, S., Higuera, J.D., Dupree, J.L., and Han, X. (2016) Novel molecular insights into the critical role of sulfatide in myelin maintenance/function. J. Neurochem. 139(1):40-54.
